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Lipid peroxidation is further amplified by lipid oxygenases (LOXs) and ROS generated through the Fenton reaction, driving the process of ferroptosis (Chen et al., 2020a)

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Therefore, the use of 18FFGln and 11C-Gln as radioactive tracers in non-invasive imaging through PET may aid in monitoring patients treatment responses, improving early diagnosis rates, and facilitating precise cancer treatment